巩方玲 研究员
  • 学历/学位: 研究生学历/博士学位
  • 研究方向: 均一可控微球微囊的制备研究、缓控释微球制剂的应用研究
  • 邮箱: gfling@ipe.ac.cn
  • 地址: 北京市海淀区中关村北二街1号
  • 邮编: 100190

简历介绍

巩方玲,研究员,博士生导师。20046月中国科学院化学研究所获得高分子化学与物理专业理学博士学位;同年7月进入中国科学院过程工程研究所生化工程国家重点实验室“生物剂型与生物材料工程”团队工作。主要研究方向有:尺寸均一、可控的聚合物微球微囊的制备与应用研究;膜乳化技术的放大规律研究;缓控释微球制剂的开发与应用研究等。主持科技部重大专项、863、国家基金、院创新项目等20多项,发表学术文章40多篇,申请发明及实用新型专利30多项,获得国家技术发明二等奖1项、中国化工学会基础研究成果奖1项、过程所青年科技创新奖3项、过程所最佳科技成果转化奖1项等。目前担任中国颗粒学会青年理事、生物颗粒专委会委员、苏州市相城区人才科技顾问等职。科研工作中发展的均一微球微囊制备技术及配套膜乳化研究装备,已在国内外多家研究机构和企业获得应用,包括英国联合利华、我国台湾和香港地区等,为微孔膜乳化技术在国际上形成重要影响做出了贡献。

代表论著

1.Yuning Hu, Dongxia Hao, Fangling Gong,?, Yuanyuan Gao, Xingran Yan, Guanghui Ma,?. Facile one-pot emulsion/sol-gel method for preparing wrinkled silicamicrospheres. Particuology, 2021, 56: 33–42.
2.Huijuan Jin, Huihui Chong, Yuanmei Zhu, Mengqiu Zhang, Xun Li, Nardana Bazybek, Yi Wei*, Fangling Gong*, Yuxian He, Guanghui Ma. Preparation and evaluation of amphipathic lipopeptide-loaded PLGA microspheres as sustained-release system for AIDS prevention, Engineering in life science, 2020, 20:476-484.
3.Xiaoqing Li, Qiang Li, Fangling Gong*, Jiandu Lei, Xi Zhao, Guanghui Ma*, Zhiguo Su. Preparation of Large-sized Highly Uniform Agarose Beads By Novel Rotating Membrane Emulsification. Journal of Membrane Sience, 2015,476:30-39.
4.Lin Zhu, Qiang Li, Fangling Gong*, Xiaofeng Yan, Xiaoqing Li, Guanghui Ma*, Zhiguo Su, Qipeng Yuan. An insight into structure regulation of uniform polystyrene micro/nano-particles by porogen in premix membrane emulsification process, Journal of Membrane Science, 2013, 448:248-255. 
5.Qiang Li, Jiandu Lei, Rongyue Zhang, Jian Li, Jianmin Xing, Fei Gao, Fangling Gong*, Xiaofeng Yan, Dan Wang, Zhiguo Su, Guanghui Ma*. Efficient decolorization and deproteinization using uniform polymer microspheres in the succinic acid biorefinery from bio-waste cotton (Gossypium hirsutum L.) stalks, Bioresource Technology, 2013, 135:604-609. 
6.Qiang Li, Rongyue Zhang, Jian Li, Xiaofeng Yan, Lianyan Wang, Fangling Gong*, Zhiguo Su, Guanghui Ma*. In situ inhibitor (HCl) removal promoted heterogeneous Friedel-Crafts reaction of polystyrene microsphere with Lewis acids catalysts, Journal of Molecular Catalysis A: Chemical, 2013, 370:56-63.  
7.Libing Mu, Zhongyuan Tu, Lin Miao, Hefei Ruan, Ning Kang, Yongzhen Hei, Jiahuan Chen, Wei Wei, Fangling Gong, Bingjie Wang, Yanan Du, Guanghui Ma, Matthias W. Amerein, Tie Xia*, Yan Shi*, A phosphatidylinositol 4,5-bisphosphate redistribution-based sensing mechanism initiates a phagocytosis programming, Nature Communications, 2018, 9: 4259.
8.Qingze Fan, Feng Qi, Chunyu Miao, Hua Yue, Fangling Gong, Jie Wu,Guanghui Ma, Zhiguo Su. Direct and controllable preparation of uniform PLGA particles with various shapes and surface morphologies, Colloids and Surfaces A: Physicochem. Eng. Aspects, 2016, 500: 177–185. 
9.Yace Mi, Weiqing Zhou, Qiang Li, Fangling Gong, Rongyue Zhang, Guanghui Ma, Zhiguo Su. Preparation of water-in-oil emulsions using a hydrophobic polymer membrane with 3D bicontinuous skeleton structure, Journal of Membrane Science, 2015, 490:113-119.
10. Fangling Gong, Guifeng Zhang, Zhiguo Su. Chapter 5 Microspheres in Separation of Bioactive Small Molecules, Microspheres and Microcapsules in Biotechnology: Design, Preparation and Applications, Pan Stanford Publishing, 2013, 153-182.