魏炜 研究员
  • 学历/学位: 研究生学历/博士学位
  • 研究方向: 生物剂型工程
  • 邮箱: weiwei@ipe.ac.cn
  • 地址: 北京市海淀区中关村北二街1号
  • 邮编: 100190

简历介绍

魏炜,中国科学院过程工程研究所研究员,博士生导师。2004年本科毕业于北京大学医学部,同年保送进入中国科学院过程工程研究所硕博连读,2011年博士毕业后留所工作至今,先后破格晋升为副研究员和研究员。研究领域主要聚焦于仿生剂型工程,重点基于蛋白、细菌、细胞等天然对象,对载体进行仿生设计,并发展新的制备过程,借助仿生对象体内固有途径实现药物精准递送,应用于抗肿瘤、疫苗、组织修复等领域。 目前,以第一/通讯作者在Nat Biomed Eng、Nat Commun、Sci Adv、Adv Mater、JACS等著名期刊发表SCI论文72篇;获中国颗粒学会自然科学一等奖(排名第1)、侯德榜化工科技青年奖、中国科学院院长特别奖、卢嘉锡青年人才奖、中国科学院优秀博士论文奖等;主持了国家基金委优秀青年基金(结题优秀)、NFSC-广东联合基金、重点研发计划课题等;担任中国化工学会生物化工青年学者工作委员会副秘书长、中国颗粒学会青年理事、中国抗癌协会青年理事等。

代表论著

1. Xiao-Ling Xie#, Yu-Xing Hu#, Tong Ye#, Yi-Ran Chen, Li-Juan Zhou, Feng Li, Xiao-Bo Xi, Shuang Wang, Yan-Jie He, Xiao-Yong Gao, Wei Wei*, Guang-Hui Ma*, Yu-Hua Li*. Therapeutic vaccination against leukaemia via the sustained release of co-encapsulated anti-PD-1 and a leukaemia-associated antigen. NATURE BIOMEDICAL ENGINEERING. DOI:10.1038/s41551-020-00624-6. online. 
2. Na-Na Luo#, Jeffrey K Weber#, Shuang Wang, Bin-Quan Luan, Hua Yue, Xiao-Bo Xi, Jing Du, Zai-Xing Yang, Wei Wei*, Ru-Hong Zhou*, Guang-Hui Ma*. PEGylated graphene oxide elicits strong immunological responses despite surface passivation. NATURE COMMUNICATIONS. 2017, 8, 14537. 
3. Xiao-Ling Wu#, Hua Yue#, Yuan-Yu Zhang#, Xiao-Yong Gao, Xiao-Yang Li, Li-Cheng Wang, Yu-Fei Cao, Miao Hou, Hai-Xia An, Lin Zhang*, Sai Li*, Jing-Yuan Ma, He Lin, Ya-Nan Fu, Hong-Kai Gu, Wen-Yong Lou, Wei Wei*, Richard N. Zare, Jun Ge*. Packaging and delivering enzymes by amorphous metal-organic frameworks. NATURE COMMUNICATIONS. 2019, 10, 5165. 
4. Yan-Lin Lv#, Feng Li#, Shuang Wang, Gui-Hong Lu, Wei-Er Bao, Yu-Gang Wang, Zhi-Yuan Tian*, Wei Wei*, Guang-Hui Ma*. Near-infrared light-triggered platelet arsenal for combined photothermal immunotherapy against cancer. SCIENCE ADVANCES. 2021, 7, eabd7614. 
5. Xiao-Bo Xi#, Tong Ye#, Shuang Wang, Xiang-Ming Na, Jiang-Hua Wang, Shuang Qing, Xiao-Yong Gao, Chang-Long Wang, Feng Li, Wei Wei*, Guang-Hui Ma*. Self-healing microcapsules synergistically modulate immunization microenvironments for potent cancer vaccination. SCIENCE ADVANCES. 2020, 6, eaay7735. 
6. Peng-Yu Chen#, Hua Yue#, Xiao-Bo Zhai, Zi-Han Huang, Guang-Hui Ma, Wei Wei*, Li-Tang Yan*. Transport of a graphene nanosheet sandwiched inside cell membranes. SCIENCE ADVANCES. 2019, 5, eaaw3192. 
7. Wei Wei, Guang-Hui Ma*, Gang Hu, Di Yu, Mcleish Tom, Zhi-Guo Su, Zhe-Yu Shen. Preparation of hierarchical hollow CaCO3 particles and the application as anticancer drug carrier. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. 2008, 130, 15808. 
8. Wei Wei, Lan Yuan, Gang Hu, Lian-Yan Wang, Hu Xue, Zhi-Guo Su, Guang-Hui Ma*. Monodisperse chitosan microspheres with interesting structures for protein drug delivery. ADVANCED MATERIALS. 2008, 20, 2292.
9. Shuang Qing, Cheng-Liang Lyu, Li Zhu, Chao Pan, Shuang Wang, Feng Li, Jiang-Hua Wang, Hua Yue, Xiao-Yong Gao, Rong-Rong Jia, Wei Wei*, Guang-Hui Ma*. Biomineralized bacterial outer membrane vesicles potentiate safe and efficient tumor microenvironment reprogramming for anticancer therapy. ADVANCED MATERIALS. 2020, 2002085. 
10. Chao Pan#, Jun Wu#, Shuang Qing#, Xiao Zhang, Lu-Lu Zhang, Hua Yue, Ming Zeng, Bin Wang, Zheng Yuan, Ye-Feng Qiu, Hua-Hu Ye, Dong-Shu Wang, Xian-Kai Liu, Peng Sun, Bo Liu, Er-Ling Feng, Xiao-Yong Gao, Li Zhu*, Wei Wei*, Guang-Hui Ma*, Heng-Liang Wang*. Biosynthesis of self-assembled proteinaceous nanoparticles for vaccination. ADVANCED MATERIALS. 2020, 9, 2002940.